Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 5/20 | 0.40 |
| ▸ | MME | P08473 | 5/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600401 | 0.86 | HSD17B10 (0.51) | HSD17B10 | |
| SCHEMBL7599734 | 0.85 | HSD17B10 (0.39) | HSD17B10KYNU | |
| SCHEMBL7598864 | 0.83 | HSD17B10 (0.53) | HSD17B10ECE1MMEACE2 | |
| SCHEMBL7598917 | 0.83 | HSD17B10 (0.37) | HSD17B10ECE1MMEACE2 | |
| SCHEMBL7598936 | 0.79 | HSD17B10 (0.49) | HSD17B10ECE1MMEACE2 | |
| SCHEMBL7598817 | 0.76 | HSD17B10 (0.44) | HSD17B10ACE2 | |
| SCHEMBL7600370 | 0.76 | HSD17B10 (0.46) | HSD17B10ECE1MMEACE2 | |
| SCHEMBL7597454 | 0.76 | HSD17B10 (0.47) | HSD17B10ECE1MMEACE2 | |
| SCHEMBL7598874 | 0.76 | HSD17B10 (0.62) | HSD17B10ECE1MMEACE2 | |
| SCHEMBL8639840 | 0.75 | NPC1 (0.40) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |
| US-5716943-A | CARDIOVASCULAR DISORDERS | ZAMBON GROUP. S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |