Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KYNU | Q16719 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598928 | 0.87 | HSD17B10 (0.47) | HSD17B10CYP3A4MMP1MMP3 | |
| SCHEMBL7600401 | 0.86 | HSD17B10 (0.51) | HSD17B10MMP1MMP3 | |
| SCHEMBL7599732 | 0.85 | F10 (0.35) | KYNUCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL7598920 | 0.85 | HSD17B10 (0.49) | HSD17B10KYNU | |
| SCHEMBL7598817 | 0.81 | HSD17B10 (0.44) | HSD17B10MMP1MMP3 | |
| SCHEMBL7598864 | 0.77 | HSD17B10 (0.53) | HSD17B10MMP1MMP3 | |
| SCHEMBL8639840 | 0.76 | NPC1 (0.40) | HSD17B10 | |
| SCHEMBL7602529 | 0.74 | HSD17B10 (0.47) | HSD17B10CYP3A4MMP1MMP3 | |
| SCHEMBL7600370 | 0.73 | HSD17B10 (0.46) | HSD17B10CYP3A4MMP1MMP3 | |
| SCHEMBL7596669 | 0.73 | KYNU (0.45) | HSD17B10KYNUALDH1A1ALOX15MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |