Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600399 | 0.85 | HSD17B10 (0.40) | HSD17B10GPR88MMEANPEPF10 | |
| SCHEMBL7599732 | 0.84 | F10 (0.35) | GPR88F10PRSS1F2 | |
| SCHEMBL7598920 | 0.83 | HSD17B10 (0.49) | HSD17B10MMEACE2ECE1 | |
| SCHEMBL8639837 | 0.74 | GPR88 (0.37) | GPR88F10PRSS1F2MEN1 | |
| SCHEMBL7598876 | 0.74 | ACE2 (0.44) | HSD17B10MMEACE2ECE1 | |
| SCHEMBL7314595 | 0.74 | PPARA (0.44) | GPR88MMEANPEPF10PRSS1 | |
| SCHEMBL7596669 | 0.73 | KYNU (0.45) | HSD17B10MMEACE2ECE1 | |
| SCHEMBL7598864 | 0.73 | HSD17B10 (0.53) | HSD17B10MMEACE2ECE1 | |
| SCHEMBL7600401 | 0.69 | HSD17B10 (0.51) | HSD17B10 | |
| SCHEMBL7598936 | 0.69 | HSD17B10 (0.49) | HSD17B10MMEACE2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |