Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598489 | 0.93 | ALDH1A1 (0.49) | ALDH1A1MGLLMAOBMAPTHTT | |
| SCHEMBL22579719 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MGLLMAOBMAPTHTT | |
| SCHEMBL8940532 | 0.83 | MAOB (0.52) | ALDH1A1MAOBMAPTHTTHTR2A | |
| SCHEMBL7541915 | 0.80 | CETP (0.52) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL7537786 | 0.80 | CETP (0.52) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL8940536 | 0.79 | MAOB (0.49) | ALDH1A1MAOBMAPTHTTHTR2A | |
| SCHEMBL5710022 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MGLLMAPTRAB9AL3MBTL1 | |
| SCHEMBL28237905 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MGLLMAPTRAB9AL3MBTL1 | |
| SCHEMBL7544051 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MGLLMAPTRAB9AL3MBTL1 | |
| SCHEMBL28667905 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200454-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009149-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |