Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940532 | 0.93 | MAOB (0.52) | MAOBALDH1A1POLBMAPTHTT | |
| SCHEMBL7598489 | 0.84 | ALDH1A1 (0.49) | MAOBALDH1A1POLBMAPTHTT | |
| SCHEMBL8672147 | 0.84 | RAB9A (0.48) | MAOBALDH1A1POLBMAPTHTT | |
| SCHEMBL7266498 | 0.84 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTRAB9AL3MBTL1 | |
| SCHEMBL2234344 | 0.83 | HTR2A (0.52) | MAOBALDH1A1MAPTHTTHTR2A | |
| SCHEMBL9976430 | 0.81 | ALDH1A1 (0.55) | MAOBALDH1A1POLBMAPTHTT | |
| SCHEMBL5603445 | 0.81 | ALDH1A1 (0.55) | MAOBALDH1A1MAPTRAB9AL3MBTL1 | |
| SCHEMBL10465087 | 0.80 | ALDH1A1 (0.54) | MAOBALDH1A1POLBMAPTHTT | |
| SCHEMBL11540661 | 0.80 | ALDH1A1 (0.54) | MAOBALDH1A1POLBMAPTHTT | |
| SCHEMBL7599200 | 0.79 | ALDH1A1 (0.49) | MAOBALDH1A1MAPTHTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583219-A | Macrocyclic chelating agent | AKZO NOBEL N.V. (NL) | 1996-12-10 | — | — | US | disclosed |
| US-5488126-A | Bifunctional chelating agents | AKZO NOBEL N.V. (NL) | 1996-01-30 | — | — | US | disclosed |
| EP-0429644-B1 | CHELATING AGENTS FOR ATTACHING METAL IONS TO PROTEINS | AKZO NOBEL NV (NL) | 1995-09-20 | — | — | EP | disclosed |
| US-5292868-A | Chelating agents for attaching metal ions to proteins | AKZO N.V. (NL) | 1994-03-08 | — | — | US | disclosed |
| EP-0429644-A4 | CHELATING AGENTS FOR ATTACHING METAL IONS TO PROTEINS | — | 1991-11-21 | — | — | EP | disclosed |
| EP-0429644-A1 | CHELATING AGENTS FOR ATTACHING METAL IONS TO PROTEINS. | AKZO NV (NL) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990014881-A2 | CHELATING AGENTS FOR ATTACHING METAL IONS TO PROTEINS | AKZO N.V. (NL) | 1990-12-13 | — | — | WO | disclosed |