Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CDC25A | P30304 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596956 | 0.85 | LMNA (0.59) | BACE1MAPTHTTALDH1A1KMT2A | |
| SCHEMBL7808779 | 0.82 | S100A4 (0.44) | MAPTALDH1A1KMT2ACDC25BSMN1; SMN2 | |
| SCHEMBL9562286 | 0.75 | CCR6 (0.62) | BACE1MAPTHTTALDH1A1KMT2A | |
| SCHEMBL21808995 | 0.75 | MAPT (0.55) | MAPTHTTALDH1A1KMT2ARAB9A | |
| SCHEMBL7598512 | 0.74 | SMN1; SMN2 (0.55) | BACE1MAPTHTTALDH1A1KMT2A | |
| SCHEMBL4190274 | 0.74 | LMNA (0.68) | MAPTHTTALDH1A1KMT2ARAB9A | |
| SCHEMBL7597626 | 0.72 | RAB9A (0.49) | MAPTHTTALDH1A1KMT2ARAB9A | |
| SCHEMBL7772483 | 0.72 | LMNA (0.70) | MAPTHTTALDH1A1KMT2ARAB9A | |
| SCHEMBL8047777 | 0.72 | BACE1 (0.50) | BACE1MAPTHTTALDH1A1KMT2A | |
| SCHEMBL7608536 | 0.71 | LMNA (0.51) | BACE1MAPTHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |