Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601156 | 0.91 | TDP1 (0.54) | TDP1HTTCA12CA1CA2 | |
| SCHEMBL7598040 | 0.87 | MTNR1B (0.51) | TDP1HTTL3MBTL1CA12CA1 | |
| SCHEMBL7603741 | 0.86 | PKM (0.50) | HTTCA12CA1CA2CA9 | |
| SCHEMBL7597973 | 0.81 | TDP1 (0.64) | TDP1HTTL3MBTL1CA12CA1 | |
| SCHEMBL7597622 | 0.80 | POLB (0.41) | TDP1HTTL3MBTL1CA12CA1 | |
| SCHEMBL7597996 | 0.80 | HTT (0.44) | TDP1HTTL3MBTL1CA12CA1 | |
| SCHEMBL7598616 | 0.79 | CA1 (0.45) | TDP1HTTL3MBTL1CA12CA1 | |
| SCHEMBL7601962 | 0.78 | MAPT (0.45) | TDP1HTTL3MBTL1CA12CA1 | |
| SCHEMBL8472237 | 0.78 | TDP1 (0.64) | TDP1HTTL3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL9862367 | 0.78 | HTT (0.60) | TDP1HTTL3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11130744-A | — | — | None | — | — | JP | disclosed |
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| JP-H11130744-A | CROSSLINKABKE COMPOUND AND OPTICAL MATERIAL USING THE SAME | MENICON CO LTD | 1999-05-18 | — | — | JP | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |