Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BHMT | Q93088 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148452 | 0.80 | LMNA (0.54) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL4609003 | 0.79 | — | — | |
| SCHEMBL7602571 | 0.79 | — | — | |
| SCHEMBL19800774 | 0.77 | BHMT (0.56) | BHMTCYP1A2GRIK1GRIK2 | |
| SCHEMBL10597019 | 0.76 | — | — | |
| SCHEMBL131849 | 0.74 | — | — | |
| E388 SCHEMBL28696 | 0.74 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28962323 | 0.74 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL10708183 | 0.73 | — | — | |
| SCHEMBL10708178 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023398-B1 | STABLE WATERBORNE POLYMER COMPOSITIONS CONTAINING POLY(ALKYLENEIMINES) | EASTMAN CHEM CO (US) | 2002-12-18 | — | — | EP | claimed |
| US-5314977-A | Graft copolymers prepared by two staged aqueous emulsion polymerization | ROHM AND HAAS COMPANY (US) | 1994-05-24 | — | — | US | claimed |
| US-5247040-A | With mercapto-olefin | ROHM AND HAAS COMPANY (US) | 1993-09-21 | — | — | US | claimed |
| US-5212251-A | Sequential emulsion polymerization of unsaturated compounds having acid-ionizable functionality to make core acid insoluble and shell acid soluble; protective coatings; inks; clear overprint varnishes; paper and fiber treatment | ROHM AND HAAS COMPANY (US) | 1993-05-18 | — | — | US | claimed |
| EP-0520668-A1 | Graft copolymers | ROHM AND HAAS COMPANY (US) | 1992-12-30 | — | — | EP | claimed |
| US-5314977-A | Graft copolymers prepared by two staged aqueous emulsion polymerization | ROHM AND HAAS COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0587333-A2 | Multi-stage polymers having alkali-soluble and alkali-insoluble stages | ROHM AND HAAS COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5247040-A | With mercapto-olefin | ROHM AND HAAS COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0520668-A1 | Graft copolymers | ROHM AND HAAS COMPANY (US) | 1992-12-30 | — | — | EP | disclosed |