Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951936 | 0.85 | ESR2 (0.61) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL2016996 | 0.81 | ESR2 (0.70) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL29662886 | 0.80 | ESR2 (0.69) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL223 | 0.80 | ESR2 (0.69) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| Water SCHEMBL3178714 | 0.80 | ESR2 (0.69) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL31410710 | 0.80 | ESR2 (0.76) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL19797926 | 0.80 | ESR2 (0.59) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL6561050 | 0.80 | ESR2 (0.59) | ESR2PTPN5GABRG2GABRB3GABRA5 | |
| SCHEMBL6561038 | 0.80 | PTPN5 (0.67) | ESR2PTPN5TRPA1ARALDH1A1 | |
| Methane SCHEMBL8312669 | 0.78 | ESR2 (0.67) | ESR2PTPN5GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020095042-A1 | Process for brominating the side chain of 4-methylbiphenyl derivatives substituted in the 2' position | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095042-A1 | Process for brominating the side chain of 4-methylbiphenyl derivatives substituted in the 2' position | CBR1, CBR3, RCOR1 | ESR2 1927/4885PTPN5 2611/4885GABRG2 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.