Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598604 | 0.85 | HTR2A (0.32) | SLC6A2SLC6A4SLC6A3KDM4EMAPT | |
| SCHEMBL797420 | 0.83 | TLR8 (0.30) | — | |
| SCHEMBL7602061 | 0.81 | HTR7 (0.39) | DHFRSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7601455 | 0.80 | DHFR (0.32) | DHFRCHRNA1CHRNGCHRNB1CHRNB2 | |
| Hydrochloric Acid SCHEMBL5616525 | 0.80 | DHFR (0.35) | DHFRCHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL797232 | 0.75 | CNR1 (0.30) | — | |
| SCHEMBL797800 | 0.74 | TLR8 (0.32) | DHFRKDM4EMAPTHTTHPGD | |
| SCHEMBL7603333 | 0.73 | MEN1 (0.38) | KDM4EMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL7607482 | 0.70 | HTR2A (0.31) | SLC6A2SLC6A4SLC6A3MAPTHTR2A | |
| Hydrochloric Acid SCHEMBL7930461 | 0.68 | CHRNA1 (0.32) | DHFRCHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |