SCHEMBL7599768

SCHEMBL7599768

O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.58
TYK2 P29597 2/20 0.54
BAZ1A Q9NRL2 1/20 0.52
MTOR P42345 1/20 0.52
KCNJ5 P48544 1/20 0.52
KCNJ3 P48549 1/20 0.52
RAB9A P51151 2/20 0.51
NPC1 O15118 2/20 0.51
TLR7 Q9NYK1 3/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
JAK2 O60674 1/20 0.50
CYP3A4 P08684 1/20 0.50
JAK1 P23458 1/20 0.50
TLR8 Q9NR97 2/20 0.49
TRPV1 Q8NER1 1/20 0.49
RORC P51449 1/20 0.49
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687933 0.92 EPHX2 (0.53) EPHX2TYK2BAZ1AMTORKCNJ5
SCHEMBL11479382 0.89 RORC (0.64) EPHX2TYK2RAB9ANPC1TLR7
SCHEMBL7603216 0.86 KDR (0.66) RAB9ATLR7MAPTNPSR1TRPV1
SCHEMBL30499683 0.86 KDR (0.66) RAB9ATLR7MAPTNPSR1TRPV1
SCHEMBL7605653 0.86 RAB9A (0.65) EPHX2RAB9ANPC1GAAMAPT
Chlotrifmeuron SCHEMBL10868747 0.84 TDP1 (0.70) EPHX2TYK2KCNJ5KCNJ3RAB9A
Penfluron SCHEMBL117735 0.84 EPHX2 (0.60) EPHX2TYK2BAZ1AMTORRAB9A
SCHEMBL7600272 0.84 GAA (0.55) TYK2RAB9ANPC1GAAMAPT
Dichlorbenzuron SCHEMBL3663126 0.83 CNR1 (0.54) EPHX2TYK2RAB9ANPC1GAA
SCHEMBL10795715 0.82 TDP1 (0.75) EPHX2RAB9ANPC1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US claimed
WO-1999016316-A1 ENHANCEMENT OF SEED YIELD OF SOYBEANS BY A SUBSTITUTED BENZOYL UREA UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-04-08 WO claimed
WO-1997045017-A1 BENZOYLUREA INSECTICIDES ON GENE-MODIFIED Bt COTTON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-04 WO claimed
EP-0193249-A2 Benzoyl urea derivatives having ati-tumor activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-09-03 EP claimed
EP-0107214-A2 Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1984-05-02 EP claimed
US-4243680-A N-(2,6-DIHALOBENZOYL)-N'-(HALOGENATED PHENYL) UREA; LARVICIDES THOMPSON-HAYWARD CHEMICAL COMPANY (US) 1981-01-06 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
US-6376430-B1 APPLYING TO CROP UNIROYAL CHEMICAL COMPANY, INC. 2002-04-23 US disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed
US-4166124-A IMIDAZOLE OR PYRIMIDINE RINGS U.S. PHILIPS CORPORATION (US) 1979-08-28 US disclosed
US-4133956-A Preparation of benzoylureas ELI LILLY AND COMPANY (US) 1979-01-09 US disclosed
US-4110469-A Insecticidal N-(2,6-dichlorobenzoyl)-N'-(4-cyanophenyl) urea U.S. PHILIPS CORPORATION (US) 1978-08-29 US disclosed
US-4013717-A BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES U.S. PHILIPS CORPORATION (US) 1977-03-22 US disclosed
US-3989842-A Certain substituted benzoyl urea insecticides U.S. PHILIPS CORPORATION (US) 1976-11-02 US disclosed
US-3933908-A INSECTICIDE U.S. PHILIPS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 EPHX2 1807/4885TYK2 1902/4885BAZ1A 386/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 EPHX2 1807/4885TYK2 1902/4885BAZ1A 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.