Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599768 | 0.92 | EPHX2 (0.58) | EPHX2BAZ1AKCNJ5KCNJ3MTOR | |
| SCHEMBL11479382 | 0.82 | RORC (0.64) | EPHX2TDP1RAB9AMAPTTLR7 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.80 | TDP1 (0.70) | EPHX2KCNJ5KCNJ3TDP1RAB9A | |
| Penfluron SCHEMBL117735 | 0.80 | EPHX2 (0.60) | EPHX2BAZ1AMTORRAB9AMAPT | |
| SCHEMBL30499683 | 0.79 | KDR (0.66) | P2RX1P2RX4P2RX7TMPRSS4RAB9A | |
| SCHEMBL7603216 | 0.79 | KDR (0.66) | P2RX1P2RX4P2RX7TMPRSS4RAB9A | |
| SCHEMBL8401785 | 0.79 | P2RX1 (0.74) | EPHX2BAZ1AP2RX1P2RX4P2RX7 | |
| SCHEMBL7605653 | 0.79 | RAB9A (0.65) | EPHX2RAB9AMAPTGAANPSR1 | |
| SCHEMBL9687352 | 0.78 | PPIA (0.59) | KCNJ5KCNJ3TDP1GAAPPIA | |
| SCHEMBL11244841 | 0.78 | MAOA (0.51) | TDP1RAB9AMAPTTYK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166180-A | Administering diphenyl substituted (thio)carbonyl(thio)urea derivatives | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-24 | — | — | US | disclosed |
| EP-0324521-A2 | Method of treating haematologic diseases and pharmaceutical compositions to be used therefor | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-07-19 | — | — | EP | disclosed |