Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | CDC25A | P30304 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599738 | 0.74 | BACE1 (0.51) | BACE1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL7598965 | 0.74 | BACE1 (0.48) | BACE1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL7600067 | 0.69 | BACE1 (0.56) | BACE1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL7602586 | 0.69 | BACE1 (0.49) | BACE1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7599782 | 0.68 | SOAT1 (0.46) | BACE1MEN1ALDH1A1GAAMAPT | |
| SCHEMBL7601683 | 0.68 | MAPK1 (0.45) | BACE1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL7597649 | 0.68 | SOAT1 (0.47) | BACE1MEN1ALDH1A1GAAMAPT | |
| SCHEMBL7598566 | 0.68 | SOAT1 (0.47) | BACE1MEN1ALDH1A1GAAMAPT | |
| SCHEMBL6555840 | 0.67 | BACE1 (0.75) | BACE1MEN1ALDH1A1LMNAGAA | |
| SCHEMBL10446297 | 0.66 | LMNA (0.58) | BACE1MEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |