SCHEMBL7600469 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TRPM8	Q7Z2W7	2/20	0.46

▸	FOLH1	Q04609	3/20	0.43

▸	PSMB5	P28074	1/20	0.42

▸	MTNR1A	P48039	4/20	0.41

▸	MTNR1B	P49286	4/20	0.41

▸	TDP1	Q9NUW8	1/20	0.40

▸	HTT	P42858	1/20	0.40

▸	SLC1A3	P43003	1/20	0.39

▸	SLC1A1	P43005	1/20	0.39

▸	EPOR	P19235	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7600355	0.92	CA1 (0.45)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7597929	0.92	CA1 (0.45)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7597839	0.91	FOLH1 (0.49)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7595812	0.91	FOLH1 (0.49)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7600882	0.90	TRPM8 (0.41)	TRPM8FOLH1PSMB5MTNR1AMTNR1B
SCHEMBL7600868	0.90	FOLH1 (0.45)	FOLH1PSMB5HTTSLC1A3SLC1A1
SCHEMBL7600890	0.89	FOLH1 (0.43)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7597117	0.88	FOLH1 (0.46)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7595116	0.88	FOLH1 (0.46)	FOLH1HTTSLC1A3SLC1A1
SCHEMBL7598385	0.88	TRPM8 (0.44)	TRPM8FOLH1PSMB5MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1017672-B1	NEW NPY ANTAGONISTS	ASTRAZENECA AB (SE)	2002-11-27	—	—	EP	disclosed