Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594433 | 0.92 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7598318 | 0.92 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7597375 | 0.92 | MAPT (0.49) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| Hydrochloric Acid SCHEMBL7600343 | 0.91 | MAPT (0.48) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7600395 | 0.89 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7594440 | 0.89 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7600469 | 0.88 | TRPM8 (0.46) | TRPM8FOLH1PSMB5MTNR1AMTNR1B | |
| SCHEMBL7595041 | 0.88 | MAPT (0.47) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7594753 | 0.88 | MAPT (0.47) | TPSAB1TPSD1TPSG1MAPTFOLH1 | |
| SCHEMBL7597561 | 0.87 | ALOX5 (0.48) | TPSAB1TPSD1TPSG1MAPTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |