Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PLD2 | O14939 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599575 | 0.78 | CA2 (0.46) | TAS1R3TAS1R1ALDH1A1HPGDLMNA | |
| SCHEMBL7598925 | 0.73 | CA1 (0.51) | TAS1R3TAS1R1ALDH1A1HPGDRAB9A | |
| SCHEMBL7600512 | 0.72 | PDE4D (0.40) | DRD2DRD4DRD3TAS1R3TAS1R1 | |
| SCHEMBL11025607 | 0.72 | TAS1R3 (0.48) | DRD2DRD4DRD3TAS1R3TAS1R1 | |
| SCHEMBL381841 | 0.68 | TAS1R3 (0.53) | TAS1R3TAS1R1ALDH1A1HPGDLMNA | |
| SCHEMBL7598279 | 0.68 | HDAC2 (0.39) | TAS1R3TAS1R1HPGDLMNARAB9A | |
| SCHEMBL13197622 | 0.67 | TAS1R3 (0.59) | TAS1R3TAS1R1ALDH1A1HPGDLMNA | |
| SCHEMBL26417166 | 0.67 | MAPK1 (0.56) | DRD2DRD4DRD3TAS1R3TAS1R1 | |
| SCHEMBL5818147 | 0.67 | HPGD (0.65) | TAS1R3TAS1R1ALDH1A1HPGDLMNA | |
| SCHEMBL12669228 | 0.67 | CA1 (0.50) | TAS1R3TAS1R1ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |