SCHEMBL26417166

SCHEMBL26417166

C=Cc1ccc(C(=O)NCCCCNC(=O)c2ccc(C=C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 1/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.51
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
POLB P06746 1/20 0.50
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
HDAC3 O15379 3/20 0.49
HDAC4 P56524 3/20 0.49
HDAC1 Q13547 3/20 0.49
HDAC7 Q8WUI4 3/20 0.49
HDAC2 Q92769 3/20 0.49
HDAC10 Q969S8 3/20 0.49
HDAC11 Q96DB2 3/20 0.49
HDAC8 Q9BY41 3/20 0.49
HDAC6 Q9UBN7 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8744962 0.98 MAPK1 (0.59) MAPK1ALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL14407383 0.89 ALDH1A1 (0.69) MAPK1ALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL1813428 0.89 MAPK1 (0.77) MAPK1ALDH1A1NPC1RAB9APOLB
SCHEMBL13593276 0.89 MAPK1 (0.77) MAPK1ALDH1A1NPC1RAB9APOLB
SCHEMBL12319407 0.89 ALDH1A1 (0.50) MAPK1ALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL19832508 0.87 POLB (0.51) MAPK1ALDH1A1TAS1R3TAS1R1POLB
SCHEMBL12855845 0.86 HPGD (0.63) ALDH1A1NPC1RAB9AL3MBTL1TAS1R3
SCHEMBL27353786 0.86 TAS1R3 (0.60) ALDH1A1NPC1RAB9AL3MBTL1TAS1R3
SCHEMBL20966259 0.86 CYP1A2 (0.62) MAPK1ALDH1A1TAS1R3TAS1R1
SCHEMBL381841 0.83 TAS1R3 (0.53) ALDH1A1RAB9ATAS1R3TAS1R1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12065516-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2024-08-20 US disclosed
US-20240052071-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORP (US) 2024-02-15 US disclosed
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed