Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.56 |
| ▸ | CA2 | P00918 | 12/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598616 | 0.85 | CA1 (0.45) | CA1CA2CA9NPC1BCL2L1 | |
| SCHEMBL7601061 | 0.83 | NPC1 (0.44) | CA1CA2CA9NPC1LMNA | |
| SCHEMBL7598975 | 0.83 | NPC1 (0.44) | CA1CA2CA9NPC1LMNA | |
| SCHEMBL28534851 | 0.81 | USP2 (0.55) | NPC1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7601359 | 0.79 | POLB (0.50) | LMNAPOLB | |
| SCHEMBL7607384 | 0.74 | PKM (0.59) | CA1CA2CA9LMNAPOLB | |
| SCHEMBL7779068 | 0.74 | CYP1A2 (0.53) | NPC1PDK1PDK2PDK3PDK4 | |
| SCHEMBL11697240 | 0.73 | CA2 (0.50) | CA1CA2CA9NPC1BCL2L1 | |
| SCHEMBL11401701 | 0.73 | POLB (0.42) | CA1CA2CA9LMNAPOLB | |
| SCHEMBL1020216 | 0.73 | CA1 (0.74) | CA1CA2CA9NPC1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |