Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598191 | 0.94 | SLC7A5 (0.44) | SLC7A5CA2CAMK2ANAALAD2POLB | |
| SCHEMBL14357545 | 0.93 | SLC7A5 (0.51) | SLC7A5CA2CAMK2ANAALAD2POLB | |
| SCHEMBL7597594 | 0.87 | CYP1A2 (0.48) | SLC7A5FOLH1 | |
| SCHEMBL8398238 | 0.85 | CYP1A2 (0.47) | SLC7A5FOLH1 | |
| SCHEMBL8597932 | 0.83 | ACE (0.43) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL7630147 | 0.82 | SLC7A5 (0.39) | SLC7A5CA2 | |
| SCHEMBL29588115 | 0.81 | CYP1A2 (0.43) | SLC7A5CA2FOLH1SLC6A2 | |
| SCHEMBL7596061 | 0.81 | CYP1A2 (0.43) | SLC7A5CA2FOLH1SLC6A2 | |
| SCHEMBL7668229 | 0.81 | CYP1A2 (0.43) | SLC7A5FOLH1SLC6A2 | |
| SCHEMBL9435308 | 0.81 | TDP1 (0.39) | CA2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | claimed |
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |