Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252487 | 1.00 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7513236 | 0.96 | TDP1 (0.40) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7598191 | 0.87 | SLC7A5 (0.44) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7596061 | 0.87 | CYP1A2 (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL29588115 | 0.87 | CYP1A2 (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL7668229 | 0.84 | CYP1A2 (0.43) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL13814004 | 0.82 | TDP1 (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL9001972 | 0.82 | TDP1 (0.40) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL530221 | 0.82 | ALDH1A1 (0.40) | ALOX15TSHR | |
| SCHEMBL9136161 | 0.82 | KCNH2 (0.49) | LMNATSHRCYP2C19CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990007342-A1 | PROCESS FOR PREPARING ISOTHIOCYANATO FUNCTIONALIZED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1990-07-12 | — | — | WO | claimed |
| EP-0374947-A1 | Process for preparing isothiocyanato functionalized metal complexes | THE DOW CHEMICAL COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| CN-101885768-B | Mercury ion antigens and preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2012-10-10 | — | — | CN | disclosed |
| CN-101885768-A | Mercury ion antigens and preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2010-11-17 | — | — | CN | disclosed |
| EP-0596011-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993002105-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1993-02-04 | — | — | WO | disclosed |
| EP-0354543-B1 | PHOTOCHEMICAL ATTACHMENT OF CHELATING GROUPS TO BIOMOLECULES | BIOMIRA, INC. (CA) | 1992-11-11 | — | — | EP | disclosed |
| US-5006643-A | Reacting aminofunctional chelates with thiophosgene | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| WO-1990007342-A1 | PROCESS FOR PREPARING ISOTHIOCYANATO FUNCTIONALIZED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1990-07-12 | — | — | WO | disclosed |
| EP-0354543-A1 | Photochemical attachment of chelating groups to biomolecules | BIOMIRA, INC. (CA) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989004375-A1 | LANTHANIDE CHELATE-TAGGED NUCLEIC ACID PROBES | SISKA DIAGNOSTICS, INC. (US) | 1989-05-18 | — | — | WO | disclosed |