Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.47 |
| ▸ | NOS2 | P35228 | 6/20 | 0.47 |
| ▸ | NOS3 | P29474 | 6/20 | 0.47 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7598762 | 0.99 | NOS1 (0.48) | NOS1NOS2NOS3QRFPR | |
| SCHEMBL7602452 | 0.94 | QRFPR (0.45) | NOS1NOS2NOS3QRFPR | |
| Hydrochloric Acid SCHEMBL7609390 | 0.93 | NOS3 (0.45) | NOS1NOS2NOS3QRFPR | |
| SCHEMBL7602077 | 0.92 | QRFPR (0.47) | NOS1NOS2NOS3QRFPR | |
| Hydrochloric Acid SCHEMBL7597176 | 0.91 | QRFPR (0.46) | NOS1NOS2NOS3QRFPR | |
| SCHEMBL7565050 | 0.88 | QRFPR (0.50) | NOS1NOS2NOS3QRFPR | |
| SCHEMBL7562881 | 0.88 | QRFPR (0.53) | NOS1NOS2NOS3QRFPR | |
| SCHEMBL7602793 | 0.87 | QRFPR (0.61) | NOS1NOS2NOS3QRFPR | |
| SCHEMBL7566374 | 0.86 | QRFPR (0.51) | NOS1NOS2NOS3QRFPR | |
| Hydrochloric Acid SCHEMBL7602398 | 0.86 | QRFPR (0.60) | NOS1NOS2NOS3QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137750-A1 | Amidine derivatives which are inhibitors of nitric oxide synthase | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | claimed |
| US-20020137750-A1 | Amidine derivatives which are inhibitors of nitric oxide synthase | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137750-A1 | Amidine derivatives which are inhibitors of nitric oxide synthase | NOS1, NOS2, NOS3 | NOS1 1/4885NOS2 2/4885NOS3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.