Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 2/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 8/20 | 0.37 |
| ▸ | CBLB | Q13191 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178051 | 0.94 | KCNJ6 (0.40) | KCNJ6KCNJ5KCNJ3METCBLB | |
| SCHEMBL1178386 | 0.91 | MET (0.41) | KCNJ6KCNJ5KCNJ3METCBLB | |
| SCHEMBL3699959 | 0.88 | KCNJ6 (0.42) | KCNJ6KCNJ5KCNJ3METCBLB | |
| SCHEMBL7601160 | 0.87 | KCNJ6 (0.38) | KCNJ6KCNJ5KCNJ3METCBLB | |
| SCHEMBL1178248 | 0.86 | KCNJ6 (0.39) | KCNJ6KCNJ5KCNJ3METCBLB | |
| Bicarbonate SCHEMBL3696258 | 0.86 | KCNJ6 (0.39) | KCNJ6KCNJ5KCNJ3METACKR3 | |
| SCHEMBL7602762 | 0.84 | CYP1A2 (0.52) | KMT2A | |
| SCHEMBL1178284 | 0.81 | MET (0.38) | KCNJ6KCNJ5KCNJ3METACKR3 | |
| SCHEMBL1177781 | 0.78 | PTGDR2 (0.37) | KMT2ATDP1 | |
| SCHEMBL7606114 | 0.78 | SMN1; SMN2 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |