SCHEMBL7601362

SCHEMBL7601362

C=C(O)CN1CCCC1=O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
HTT P42858 1/20 0.51
KMT2A Q03164 2/20 0.49
PIK3CD O00329 1/20 0.47
CYP1A2 P05177 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CYP2D6 P10635 1/20 0.43
CHRM1 P11229 1/20 0.43
CYP2C9 P11712 1/20 0.43
CHRM3 P20309 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 1/20 0.42
BLM P54132 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11760214 0.82 TSHR (0.59) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL22446137 0.82 TSHR (0.69) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL6775348 0.82 TSHR (0.58) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL917410 0.82 TSHR (0.58) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL948990 0.81 TSHR (0.68) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL20437773 0.79 TSHR (0.55) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL18407882 0.79 TSHR (0.59) TSHRHTTKMT2APIK3CDCYP1A2
Piracetam SCHEMBL6140872 0.75 TSHR (1.00) TSHRHTTKMT2APIK3CDCYP1A2
Piracetam SCHEMBL20172 0.75 TSHR (1.00) TSHRHTTKMT2APIK3CDCYP1A2
SCHEMBL18455388 0.75 TSHR (0.66) TSHRHTTKMT2APIK3CDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023345-B1 RESINS FROM N-ALKENYL AMIDES AND ALLYLIC MONOMERS ARCO CHEM TECH (US) 2002-11-27 EP claimed
US-5721200-A REACTING OLEFINIC COPLYMER WITH UNSATURATED ACYLATING AGENT TO FROM A GRAFT COPOLYMER AND REDUCING MOLECULAR WEIGHT, REACTING GRAFTED COPOLYMER WITH AMINO-ALCOHOL COMPOUND DSM COPOLYMER, INC. (US) 1998-02-24 US claimed
US-5474694-A Dispersant additive which is an modified alpha-olefin polymer TEXACO INC. (US) 1995-12-12 US claimed
US-5721200-A REACTING OLEFINIC COPLYMER WITH UNSATURATED ACYLATING AGENT TO FROM A GRAFT COPOLYMER AND REDUCING MOLECULAR WEIGHT, REACTING GRAFTED COPOLYMER WITH AMINO-ALCOHOL COMPOUND DSM COPOLYMER, INC. (US) 1998-02-24 US disclosed
US-5474694-A Dispersant additive which is an modified alpha-olefin polymer TEXACO INC. (US) 1995-12-12 US disclosed