Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598974 | 0.91 | KMT2A (0.41) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL7601352 | 0.90 | KMT2A (0.41) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL7597627 | 0.89 | KMT2A (0.40) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL8105519 | 0.87 | KMT2A (0.40) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL8097649 | 0.85 | LMNA (0.39) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL7602577 | 0.81 | POLB (0.46) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL7602558 | 0.80 | POLB (0.46) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL7597987 | 0.80 | L3MBTL1 (0.36) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL7596376 | 0.79 | POLB (0.47) | KMT2APOLBL3MBTL1ATMTDP1 | |
| SCHEMBL8111065 | 0.79 | POLB (0.49) | KMT2APOLBL3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |