Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601427 | 0.90 | MTNR1B (0.40) | LMNAALDH1A1MAPTHTTPKM | |
| SCHEMBL7598974 | 0.87 | KMT2A (0.41) | LMNAALDH1A1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL7601352 | 0.86 | KMT2A (0.41) | LMNAALDH1A1MAPTPKMSMN1; SMN2 | |
| SCHEMBL7597627 | 0.85 | KMT2A (0.40) | ALDH1A1SMN1; SMN2L3MBTL1POLBATM | |
| SCHEMBL7601403 | 0.85 | KMT2A (0.40) | ALDH1A1SMN1; SMN2L3MBTL1POLBATM | |
| SCHEMBL8105519 | 0.85 | KMT2A (0.40) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7602577 | 0.83 | POLB (0.46) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7597987 | 0.81 | L3MBTL1 (0.36) | LMNAALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8111065 | 0.80 | POLB (0.49) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7596376 | 0.80 | POLB (0.47) | LMNAALDH1A1MAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |