Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760141 | 0.81 | PDE4B (0.56) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL460455 | 0.81 | HSD17B2 (0.77) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL25386030 | 0.75 | HSD17B2 (0.62) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10422057 | 0.73 | HSD17B2 (0.64) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL20116491 | 0.73 | PDE4B (0.56) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL703602 | 0.71 | CA12 (0.64) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL662208 | 0.71 | MEN1 (0.60) | HSD17B2PDE4BPDE4APDE4CPDE4D | |
| Isovanillic Acid Methyl Ester SCHEMBL29497236 | 0.71 | CA1 (0.69) | HSD17B2PDE4DCA12CA1CA2 | |
| Isovanillic Acid Methyl Ester SCHEMBL57367 | 0.71 | CA1 (0.69) | HSD17B2PDE4DCA12CA1CA2 | |
| SCHEMBL8733776 | 0.70 | GAA (0.63) | HSD17B2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217093-B1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2012-03-21 | — | — | EP | disclosed |