Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600372 | 0.90 | CA1 (0.39) | FOLH1CA1CA2ACHEDPP8 | |
| SCHEMBL7600355 | 0.89 | CA1 (0.45) | FOLH1CA1CA2ACHEDPP8 | |
| SCHEMBL7597929 | 0.89 | CA1 (0.45) | FOLH1CA1CA2ACHEDPP8 | |
| SCHEMBL7595770 | 0.88 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL7596349 | 0.87 | TPSAB1 (0.44) | FOLH1CA1CA2ACHEDPP8 | |
| SCHEMBL7595801 | 0.87 | FOLH1 (0.43) | FOLH1CA1CA2ACHEDPP8 | |
| SCHEMBL7600358 | 0.87 | FOLH1 (0.43) | FOLH1CA1CA2ACHEDPP8 | |
| SCHEMBL7600868 | 0.83 | FOLH1 (0.45) | FOLH1DPP8DPP7HTTSLC1A3 | |
| Hydrochloric Acid SCHEMBL7595130 | 0.83 | ALDH1A1 (0.40) | CNR1CNR2 | |
| SCHEMBL7595812 | 0.83 | FOLH1 (0.49) | FOLH1DPP8DPP7KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |