Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16907942 | 0.93 | TSHR (0.50) | TSHRCNR1NAAAPOLBTP53 | |
| SCHEMBL18164189 | 0.87 | TSHR (0.55) | TSHRNAAAPOLBRECQLDNM1 | |
| SCHEMBL27805033 | 0.86 | CASP2 (0.52) | TSHRCNR1NAAAL3MBTL1DNM1 | |
| SCHEMBL22174072 | 0.85 | TSHR (0.52) | TSHRNAAAPOLBL3MBTL1RECQL | |
| SCHEMBL31074224 | 0.84 | TSHR (0.52) | TSHRNAAAPOLBRECQLDNM1 | |
| SCHEMBL25801633 | 0.82 | CASP2 (0.52) | TSHRCNR1NAAAL3MBTL1DNM1 | |
| SCHEMBL27628884 | 0.82 | TSHR (0.46) | TSHRPOLBRECQLCASP2FAAH | |
| SCHEMBL19083849 | 0.80 | CASP2 (0.58) | TSHRNAAACASP2FAAH | |
| SCHEMBL16422261 | 0.79 | TSHR (0.41) | TSHRNAAAPOLBCASP2FAAH | |
| SCHEMBL24844352 | 0.79 | EPHX2 (0.51) | TSHRCNR1POLBMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028455-A1 | Methods and reagents for assembling molecules on solid supports | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-03-07 | — | — | US | disclosed |
| WO-2001083826-A2 | METHODS AND REAGENTS FOR ASSEMBLING MOLECULES ON SOLID SUPPORTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-11-08 | — | — | WO | disclosed |