Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 8/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602771 | 0.94 | SMN1; SMN2 (0.43) | PTGESPTGS2SMN1; SMN2 | |
| SCHEMBL7601064 | 0.90 | PTGES (0.59) | PTGESPTGS2SMN1; SMN2 | |
| SCHEMBL7601258 | 0.88 | PTGES (0.52) | PTGESPTGS2SMN1; SMN2 | |
| SCHEMBL1080100 | 0.87 | PTGES (0.46) | PTGESPTGS2 | |
| SCHEMBL1178083 | 0.81 | PTGES (0.47) | PTGESPTGS2 | |
| SCHEMBL1178773 | 0.80 | PTGES (0.40) | PTGESPTGS2 | |
| SCHEMBL7606114 | 0.80 | SMN1; SMN2 (0.44) | PTGESSMN1; SMN2 | |
| SCHEMBL1178359 | 0.80 | PTGES (0.39) | PTGESPTGS2 | |
| SCHEMBL13660722 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2 | |
| SCHEMBL1178752 | 0.79 | PTGES (0.49) | PTGESPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |