Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 12/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601258 | 0.94 | PTGES (0.52) | PTGESSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL7602037 | 0.90 | PTGES (0.47) | PTGESSMN1; SMN2PTGS2 | |
| SCHEMBL1082090 | 0.87 | PTGES (0.58) | PTGESPTGS2 | |
| SCHEMBL7605706 | 0.85 | PARP1 (0.48) | PTGESSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL7602771 | 0.84 | SMN1; SMN2 (0.43) | PTGESSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1081379 | 0.81 | PTGES (0.51) | PTGESPTGS2 | |
| SCHEMBL1081838 | 0.80 | PTGES (0.50) | PTGESPTGS2 | |
| SCHEMBL7602721 | 0.80 | PGR (0.41) | PTGESSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL7601260 | 0.80 | PGR (0.41) | PTGESSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1178752 | 0.80 | PTGES (0.49) | PTGESPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |