Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA2 | P54652 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 4/20 | 0.42 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601979 | 0.90 | HSPA2 (0.46) | HSPA2ADORA3ADORA2ATRPM2SLC28A2 | |
| SCHEMBL1881041 | 0.84 | POLB (0.52) | TRPM2FBP1 | |
| SCHEMBL8917329 | 0.83 | ADORA3 (0.55) | ADORA3ADORA2ASLC28A2HSPA8HSPA5 | |
| SCHEMBL7599209 | 0.83 | ADORA3 (0.55) | ADORA3ADORA2ASLC28A2HSPA8HSPA5 | |
| SCHEMBL1887064 | 0.81 | TRPM2 (0.56) | TRPM2 | |
| SCHEMBL7042426 | 0.81 | TRPM2 (0.56) | TRPM2 | |
| SCHEMBL6762581 | 0.79 | ADORA3 (0.59) | ADORA3ADORA2ASLC28A2HSPA8FBP1 | |
| SCHEMBL6762570 | 0.79 | ADORA3 (0.59) | ADORA3ADORA2ASLC28A2HSPA8FBP1 | |
| SCHEMBL6762489 | 0.78 | ADORA3 (0.60) | ADORA3ADORA2ASLC28A2HSPA8FBP1 | |
| SCHEMBL6762479 | 0.78 | ADORA3 (0.60) | ADORA3ADORA2ASLC28A2HSPA8FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135587-B2 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS | SYNGENE INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0135587-B1 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS | SYNGENE, INC. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0135587-A4 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. | MOLECULAR BIOSYSTEMS INC (US) | 1986-04-02 | — | — | EP | disclosed |
| EP-0135587-A1 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. | MOLECULAR BIOSYSTEMS INC (US) | 1985-04-03 | — | — | EP | disclosed |
| WO-1984003285-A1 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS | MOLECULAR BIOSYSTEMS INC (US) | 1984-08-30 | — | — | WO | disclosed |