Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CTRC | Q99895 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068486 | 0.82 | KDM4E (0.59) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL3068503 | 0.82 | KDM4E (0.59) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL3072317 | 0.82 | CTRC (0.62) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL3072320 | 0.82 | CTRC (0.62) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL7063429 | 0.79 | CTRC (0.69) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL12955480 | 0.78 | KMT2A (0.61) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL20328565 | 0.78 | KMT2A (0.61) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL734790 | 0.74 | KMT2A (1.00) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL734791 | 0.74 | KMT2A (1.00) | KMT2AMEN1HPGDALDH1A1MAPT | |
| SCHEMBL15457449 | 0.74 | L3MBTL1 (0.74) | KMT2AMEN1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752813-B1 | INHIBITORS OF METAZOAN PARASITE PROTEASES | UNIV CALIFORNIA (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-0752813-A4 | INHIBITORS OF METAZOAN PARASITE PROTEASES | UNIV CALIFORNIA (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5610192-A | Inhibitors of metazoan parasite proteases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0752813-A1 | INHIBITORS OF METAZOAN PARASITE PROTEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1994006280-A1 | INHIBITORS OF METAZOAN PARASITE PROTEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-31 | — | — | WO | disclosed |