SCHEMBL7602479

SCHEMBL7602479

CC(C)(C)OC(=O)OC1c2ccccc2Oc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.47
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
ATM Q13315 2/20 0.44
NR3C1 P04150 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
USP2 O75604 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596808 0.82 POLB (0.47) HDAC3HDAC4HDAC7HDAC8HDAC6
SCHEMBL5730818 0.82 L3MBTL1 (0.50) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL7555796 0.78 ATM (0.50) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL7945050 0.78 ATM (0.55) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL5731331 0.76 ATM (0.52) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL7837312 0.75 ATM (0.50) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL7561924 0.74 TSHR (0.47) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL11728672 0.74 HDAC3 (0.47) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL27773729 0.72 CYP2C9 (0.47) PKMHDAC3HDAC4HDAC1HDAC7
SCHEMBL26419663 0.72 GPR119 (0.38) PKMATMMEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874281-B1 Chemically amplified resist INFINEON TECHNOLOGIES AG (DE) 2002-12-04 EP disclosed
EP-0874281-A1 Chemically amplified resist SIEMENS AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed