Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600285 | 0.97 | PPARA (0.57) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL7600290 | 0.89 | PPARA (0.59) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL2692877 | 0.86 | PPARA (0.56) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL7803935 | 0.83 | PPARA (0.41) | PPARAPPARGFFAR1CYP1A2CYP2C19 | |
| SCHEMBL19470214 | 0.81 | PPARA (0.42) | PPARAPPARGCA12CA1CA2 | |
| Acetic Acid SCHEMBL9578985 | 0.78 | CA12 (0.54) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL7602708 | 0.78 | HPGD (0.51) | PPARAPPARGACACBACACA | |
| SCHEMBL21790492 | 0.77 | KMT2A (0.50) | PPARGCYP1A2GAACYP2C9PKM | |
| SCHEMBL22003014 | 0.77 | HPGD (0.55) | PPARAPPARG | |
| SCHEMBL2035474 | 0.77 | CA12 (0.54) | PPARAPPARGCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482877-B2 | MELT PROCESSABILITY; MIXTURE WITH PHOSPHOROUS ACID, SULFUR COMPOUND AND FATTY ESTER | GENERAL ELECTRIC COMPANY | 2002-11-19 | — | — | US | disclosed |
| EP-1156078-A1 | Polycarbonate resin composition for optical use | GENERAL ELECTRIC COMPANY (US) | 2001-11-21 | — | — | EP | disclosed |
| US-20010041759-A1 | Polycarbonate resin composition for optical use | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2001-11-15 | — | — | US | disclosed |