Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600290 | 0.90 | PPARA (0.59) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL7600285 | 0.89 | PPARA (0.57) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL7602715 | 0.86 | PPARA (0.58) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL4185139 | 0.84 | GAPDH (0.49) | ELANEBACE1HSD17B10MAPTGAA | |
| Acetic Acid SCHEMBL9578985 | 0.79 | CA12 (0.54) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL1551128 | 0.78 | LMNA (0.55) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL9788610 | 0.78 | BACE1 (0.56) | ELANEBACE1HSD17B10MAPTGAA | |
| SCHEMBL12172262 | 0.78 | MAPT (0.55) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL13913541 | 0.78 | ABL1 (0.56) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL3785193 | 0.77 | ELANE (0.51) | ELANEBACE1HSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567281-B2 | 4-acylaralkylphenols and derivatives thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9090547-B2 | Method for producing trisphenols and monoester-substituted products thereof, and 4-acylaralkylphenol derivatives | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-0269321-B1 | LIQUID CRYSTAL COPOLYESTERS HAVING A BLOCKED TERMINAL OF ITS MOLECULAR CHAIN | POLYPLASTICS CO. LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-4904752-A | Liquid crystal copolyester having blocked molecular chain terminal | POLYPLASTICS CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0269321-A2 | Liquid crystal copolyesters having a blocked terminal of its molecular chain | POLYPLASTICS CO. LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | UGT1A7, CYP19A1, UGT2B7 | PPARA 132/4885PPARG 110/4885CA12 4159/4885 |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | CYP19A1, MTTP, CYP4X1 | PPARA 580/4885PPARG 283/4885CA12 2593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.