SCHEMBL22003014

SCHEMBL22003014

O=C(Oc1ccccc1)Oc1ccc(-c2ccccc2O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 2/20 0.55
BCL2L1 Q07817 1/20 0.55
ALOX15 P16050 1/20 0.49
ESR2 Q92731 1/20 0.43
NSD2 O96028 1/20 0.42
GSTP1 P09211 1/20 0.42
MAOA P21397 2/20 0.41
ADAMTS4 O75173 1/20 0.40
PPARG P37231 2/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
NCOA2 Q15596 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
BACE1 P56817 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylphenol SCHEMBL246847 0.95 HPGD (0.63) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL21785663 0.85 HPGD (0.50) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
2-Phenylphenol SCHEMBL246850 0.84 HPGD (0.63) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL21790492 0.82 KMT2A (0.50) HPGDHSD17B10ALDH1A1ALOX15PPARG
SCHEMBL1674296 0.81 HPGD (0.46) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL246849 0.81 KMT2A (0.53) HSD17B10ALDH1A1PPARGMAPTKMT2A
SCHEMBL1624304 0.80 KMT2A (0.52) HPGDHSD17B10ALDH1A1ALOX15NSD2
SCHEMBL21790491 0.79 MMP3 (0.54) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL21790493 0.79 MMP3 (0.54) HPGDHSD17B10ALDH1A1BCL2L1ALOX15
SCHEMBL23161028 0.79 HPGD (0.47) HPGDHSD17B10ALDH1A1BCL2L1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118009-B2 Aromatic polycarbonate oligomer solid HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-14 US disclosed
US-20210054142-A1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-02-25 US disclosed
US-10655010-B2 Aromatic polycarbonate oligomer solid HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2020-05-19 US disclosed