SCHEMBL760290

SCHEMBL760290

CC(=O)c1ccc(C)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
HPGD P15428 2/20 0.57
CYP3A4 P08684 1/20 0.57
MAPK1 P28482 1/20 0.57
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
TRPA1 O75762 1/20 0.52
CSNK2A1 P68400 1/20 0.52
IDO1 P14902 2/20 0.51
TDO2 P48775 2/20 0.51
PLG P00747 3/20 0.50
KLK1 P06870 2/20 0.50
KLK6 Q92876 2/20 0.50
F2 P00734 1/20 0.49
F10 P00742 1/20 0.49
PLAU P00749 1/20 0.49
PLAT P00750 1/20 0.49
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
TAS1R2 Q8TE23 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495480 1.00 ALDH1A1 (0.57) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL30578000 0.84 NPC1 (0.56) ALDH1A1HPGDCYP3A4NPC1RAB9A
SCHEMBL1758035 0.84 NPC1 (0.56) ALDH1A1HPGDCYP3A4NPC1RAB9A
SCHEMBL15761520 0.83 IDO1 (0.50) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL6856523 0.82 NPC1 (0.55) ALDH1A1HPGDNPC1RAB9ATRPA1
SCHEMBL168869 0.82 CSNK2A1 (0.69) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL29495347 0.82 CSNK2A1 (0.69) ALDH1A1RAB9ATRPA1CSNK2A1F2
SCHEMBL471440 0.82 CSNK2A1 (0.69) ALDH1A1RAB9ATRPA1CSNK2A1F2
SCHEMBL12986352 0.81 CSNK2A1 (0.50) ALDH1A1HPGDCYP3A4MAPK1NPC1
Ammonia Solution, Strong SCHEMBL25336824 0.80 CSNK2A1 (0.67) ALDH1A1HPGDCYP3A4MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978919-A Antibacterial coating and preparation method thereof 抚顺世茂新材料科技有限公司 2025-05-13 CN claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
EP-3253750-B1 NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2019-04-10 EP claimed
US-10221165-B2 Flavone based EGFR inhibitors and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2019-03-05 US claimed
US-20180016268-A1 Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-01-18 US claimed
WO-2016125186-A1 NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-08-11 WO claimed
EP-0031253-B1 PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP claimed
US-4335263-A MANY STEPS, STARTING WITH ACETYLATION OF M-CRESOL OR P-CRESOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-15 US claimed
EP-0031253-A1 Process for preparing 3,4-substituted benzaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-01 EP claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed
CN-120022203-A Triazole derivatives of kojic acid with tyrosinase inhibitory activity, alpha-glucosidase inhibitory activity and antioxidant activity 邵阳学院 2025-05-23 CN disclosed
CN-119978919-A Antibacterial coating and preparation method thereof 抚顺世茂新材料科技有限公司 2025-05-13 CN disclosed
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF SPARK BIOPHARMA, INC. (KR) 2025-02-06 US disclosed
CN-115605476-B Substituted tricyclic compounds 鲁宾有限公司 2024-05-24 CN disclosed
EP-0031253-B1 PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP disclosed
US-4335263-A MANY STEPS, STARTING WITH ACETYLATION OF M-CRESOL OR P-CRESOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-15 US disclosed
EP-0031253-A1 Process for preparing 3,4-substituted benzaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-01 EP disclosed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US disclosed
US-4002423-A Benzofuran derivatives process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF MYD88, MYADM, CD14 ALDH1A1 2146/4885HPGD 229/4885CYP3A4 428/4885
US-20180016268-A1 Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof EGFR, ERBB2, ABL1 ALDH1A1 1959/4885HPGD 3824/4885CYP3A4 1572/4885
US-10221165-B2 Flavone based EGFR inhibitors and process for preparation thereof EGFR, ERBB2, ABL1 ALDH1A1 2054/4885HPGD 3869/4885CYP3A4 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.