Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7603494 | 0.83 | HTR1A (0.74) | HTR1AHTR7DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7608421 | 0.83 | HTR1A (0.74) | HTR1AHTR7DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7607604 | 0.83 | HTR1A (0.74) | HTR1AHTR7DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7608424 | 0.82 | HTR1A (0.76) | HTR1AHTR7DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL6542136 | 0.79 | HTR1A (0.72) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL14591459 | 0.79 | DRD2 (0.59) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL14591458 | 0.79 | DRD2 (0.59) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL14591336 | 0.79 | DRD2 (0.59) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL14591372 | 0.79 | DRD2 (0.59) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL9183738 | 0.77 | DRD2 (0.58) | HTR1AHTR7DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065312-A1 | Aminotetralins as 5-HT1Dalpha agonists | SCHAUS JOHN M (US) | 2002-05-30 | — | — | US | disclosed |
| US-6355674-B1 | PSYCHOLOGICAL DISORDERS; ANTISEROTONINE AGENTS | ELI LILLY AND COMPANY | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065312-A1 | Aminotetralins as 5-HT1Dalpha agonists | HTR1D, HTR1A, HTR1E | HTR1A 2/4885HTR7 10/4885DRD2 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.