Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447642 | 0.85 | ADRA2C (0.30) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL7598778 | 0.81 | BRD4 (0.33) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL797922 | 0.80 | BCHE (0.36) | BCHEACHE | |
| SCHEMBL7602766 | 0.77 | ADRA2C (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL7602958 | 0.75 | HTT (0.32) | — | |
| SCHEMBL7607516 | 0.73 | HTR2A (0.33) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL6895735 | 0.72 | ADRA2C (0.32) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL7603401 | 0.71 | — | — | |
| SCHEMBL796719 | 0.68 | BCHE (0.36) | BCHEACHE | |
| SCHEMBL7599303 | 0.68 | HTR7 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |