Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796719 | 0.80 | BCHE (0.36) | BCHEACHESIGMAR1 | |
| SCHEMBL7607809 | 0.77 | ADRA2C (0.33) | HRH1ADRA2CPTGS2HTR3APDE4D | |
| SCHEMBL7602945 | 0.73 | ADRA2C (0.31) | CYP19A1CYP11B1CYP11B2HRH1ADRA2C | |
| SCHEMBL4447642 | 0.72 | ADRA2C (0.30) | HRH1ADRA2CPTGS2HTR3APDE4D | |
| SCHEMBL7604203 | 0.71 | — | — | |
| SCHEMBL797922 | 0.68 | BCHE (0.36) | BCHEACHESIGMAR1 | |
| SCHEMBL796457 | 0.66 | BCHE (0.36) | BCHEACHE | |
| SCHEMBL7602016 | 0.65 | HTR1A (0.33) | SIGMAR1 | |
| SCHEMBL7599331 | 0.63 | HTR1A (0.34) | CYP11B2ADRA2CSIGMAR1 | |
| SCHEMBL7061765 | 0.61 | HTR2A (0.37) | HTR2AHRH1ADRA2CPTGS2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |