SCHEMBL7602959

SCHEMBL7602959

FC(=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29905593 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL9424657 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL320598 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL333072 0.97 THRB (0.42) THRBLMNA
SCHEMBL333073 0.97 THRB (0.42) THRBLMNA
SCHEMBL9211057 0.97 THRB (0.42) THRBLMNA
Ethane SCHEMBL28051354 0.95 THRB (0.42) THRBLMNA
SCHEMBL8380164 0.91 THRB (0.52) THRBLMNACA1CA2MMP1
SCHEMBL5374510 0.91 THRB (0.52) THRBLMNACA1CA2MMP1
SCHEMBL5365862 0.91 THRB (0.52) THRBLMNACA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119261336-A Self-water-absorbing structure water-retaining soil moisture-preserving biodegradable agricultural film and preparation method thereof 江苏智信塑胶科技有限公司 2025-01-07 CN disclosed
CN-109593451-A Bisphenol AF base hydrophobic oleophobic non-isocyanate polyurethane coating and the preparation method and application thereof 华南理工大学 2019-04-09 CN disclosed
EP-0755960-B1 Polyfunctional perfluorinated polyorganosiloxanes and processes for their preparation RHODIA CHIMIE SA (FR) 2002-11-27 EP disclosed
US-6197987-B1 Polyfunctional perhalogenated polyorganosiloxanes and the processes for their preparation RHONE-BOULING CHIMIE (FR) 2001-03-06 US disclosed
US-6184329-B1 USED IN ANTIFOAMS, AGENTS FOR LOWERING SURFACE TENSION, DIRT REPELLENTS, ANTIADHESIVES, LUBRICANTS, OLEOPHOBIC AND/OR HYDROPHOBIC AGENTS, COATINGS; STABILITY RHONE-POULENC CHIMIE (FR) 2001-02-06 US disclosed
EP-0755960-A1 Polyfunctional perhalogenated polyorganosiloxanes and processes for their preparation RHONE-POULENC CHIMIE (FR) 1997-01-29 EP disclosed