SCHEMBL320598

SCHEMBL320598

FC(=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29905593 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL7602959 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL9424657 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL333072 0.97 THRB (0.42) THRBLMNA
SCHEMBL333073 0.97 THRB (0.42) THRBLMNA
SCHEMBL9211057 0.97 THRB (0.42) THRBLMNA
Ethane SCHEMBL28051354 0.95 THRB (0.42) THRBLMNA
SCHEMBL8380164 0.91 THRB (0.52) THRBLMNACA1CA2MMP1
SCHEMBL5374510 0.91 THRB (0.52) THRBLMNACA1CA2MMP1
SCHEMBL5365862 0.91 THRB (0.52) THRBLMNACA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018165608-A1 PROCESSES FOR PREPARING PARTIALLY FLUORINATED EPOXIDES AND PERFLUORINATED EPOXIDES AND COMPOSITIONS RELATED THERETO THE CHEMOURS COMPANY FC, LLC (US) 2018-09-13 WO claimed
CN-105637059-A Use of alkyl perfluoroalkene ethers and mixtures thereof in high temperature heat pumps CHEMOURS CO FC LLC 2016-06-01 CN claimed
CN-103827069-B The method of separated portion in alkyl perfluoroolefine ether is produced E. I. DU PONT DE NEMOURS AND CO. (US) 2016-04-06 CN claimed
EP-2760814-B1 PROCESSES FOR SEPARATING COMPONENTS IN ALKYL PERFLUOROALKENE ETHER PRODUCTION DU PONT (US) 2015-10-28 EP claimed
EP-2760814-A1 PROCESSES FOR SEPARATING COMPONENTS IN ALKYL PERFLUOROALKENE ETHER PRODUCTION E. I. Du Pont de Nemours and Company (US) 2014-08-06 EP claimed
CN-103827069-A Processes for separating components in alkyl perfluoroalkene ether production DU PONT 2014-05-28 CN claimed
US-8592630-B2 Processes for separating components in alkyl perfluoroalkene ether production E I DU PONT DE NEMOURS AND COMPANY (US) 2013-11-26 US claimed
WO-2013086264-A1 COMPOSITION COMPRISING FLUOROALKYL PERFLUOROALKENE ETHERS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-13 WO claimed
WO-2013049245-A1 PROCESSES FOR SEPARATING COMPONENTS IN ALKYL PERFLUOROALKENE ETHER PRODUCTION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-04-04 WO claimed
US-20130079558-A1 PROCESSES FOR SEPARATING COMPONENTS IN ALKYL PERFLUOROALKENE ETHER PRODUCTION E I DU PONT DE NEMOURS AND COMPANY (US) 2013-03-28 US claimed
CN-102317245-A Novel alkyl perfluoroalkene ethers and uses thereof DU PONT 2012-01-11 CN claimed
EP-2396294-A2 NOVEL ALKYL PERFLUOROALKENE ETHERS AND USES THEREOF E. I. du Pont de Nemours and Company (US) 2011-12-21 EP claimed
US-20110282104-A1 NOVEL ALKYL PERFLUOROALKENE ETHERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-17 US claimed
US-20100209600-A1 NOVEL ALKYL PERFLUOROALKENE ETHERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 US claimed
WO-2010094019-A2 NOVEL ALKYL PERFLUOROALKENE ETHERS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 WO claimed
US-20210139441-A1 USES OF FLUORINATED EPOXIDES AND NOVEL MIXTURES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-05-13 US disclosed
US-20190211247-A1 Use of Alkyl Perfluoroalkene Ethers and Mixtures Thereof in High Temperature Heat Pumps JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2019-07-11 US disclosed
US-5268122-A Azeotropic mixture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-07 US disclosed
CN-1070903-A Gm-dihydropolyfluoroalkanes and preparation method thereof and cleaning use DU PONT (US) 1993-04-14 CN disclosed
WO-1993005002-A2 GEM-DIHYDROPOLYFLUOROALKANES AND MONOHYDROPOLYFLUOROALKENES, PROCESSES FOR THEIR PRODUCTION, AND USE OF GEM-DIHYDROPOLYFLUOROALKANES IN CLEANING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139441-A1 USES OF FLUORINATED EPOXIDES AND NOVEL MIXTURES THEREOF PFAS, PFN1, FRG1 THRB 3866/4885LMNA 3631/4885CA1 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.