SCHEMBL9424657

SCHEMBL9424657

FC(=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29905593 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL7602959 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL320598 1.00 THRB (0.46) THRBLMNACA1CA2MMP1
SCHEMBL333072 0.97 THRB (0.42) THRBLMNA
SCHEMBL333073 0.97 THRB (0.42) THRBLMNA
SCHEMBL9211057 0.97 THRB (0.42) THRBLMNA
Ethane SCHEMBL28051354 0.95 THRB (0.42) THRBLMNA
SCHEMBL8380164 0.91 THRB (0.52) THRBLMNACA1CA2MMP1
SCHEMBL5374510 0.91 THRB (0.52) THRBLMNACA1CA2MMP1
SCHEMBL5365862 0.91 THRB (0.52) THRBLMNACA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013086264-A1 COMPOSITION COMPRISING FLUOROALKYL PERFLUOROALKENE ETHERS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-13 WO claimed
US-11427907-B2 Gas supply apparatus and gas supply method SHOWA DENKO K.K. (JP) 2022-08-30 US disclosed
WO-2013086264-A1 COMPOSITION COMPRISING FLUOROALKYL PERFLUOROALKENE ETHERS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-13 WO disclosed
US-5331084-A Chemical intermediates for polyethers HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed