Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797631 | 0.74 | BCHE (0.38) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL8676094 | 0.70 | MEN1 (0.33) | GPR3KDM4EHTR2ACYP2D6LMNA | |
| SCHEMBL7065768 | 0.68 | HTR2A (0.33) | GPR3KDM4EHTR2ACYP2D6LMNA | |
| SCHEMBL29386036 | 0.67 | HTR2A (0.39) | GPR3KDM4EHTR2ACYP2D6LMNA | |
| SCHEMBL19630560 | 0.67 | HTR2A (0.39) | GPR3KDM4EHTR2ACYP2D6LMNA | |
| Chloromethane SCHEMBL3689975 | 0.67 | SIGMAR1 (0.34) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL29758162 | 0.66 | HTR2A (0.38) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL2136144 | 0.66 | HTR2A (0.38) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL6763868 | 0.66 | HTR2A (0.38) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL8857133 | 0.66 | HTR2A (0.33) | GPR3KDM4EHTR2ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| US-6255531-B1 | POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |