Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17963707 | 0.85 | GAA (0.49) | GAAALDH1A1AOX1TRPV1TUBB1 | |
| SCHEMBL14243146 | 0.80 | APP (0.50) | GAAALDH1A1AOX1TRPV1TUBB1 | |
| SCHEMBL30135395 | 0.80 | ALDH1A1 (0.59) | GAAALDH1A1AOX1TRPV1TUBB1 | |
| SCHEMBL420149 | 0.80 | ALDH1A1 (0.59) | GAAALDH1A1AOX1TRPV1TUBB1 | |
| SCHEMBL6337285 | 0.79 | GAA (0.54) | GAAALDH1A1AOX1TRPV1TUBB1 | |
| SCHEMBL14167825 | 0.76 | CYP19A1 (0.50) | GAAALDH1A1AOX1TUBB1TUBB4A | |
| SCHEMBL1331644 | 0.74 | L3MBTL1 (0.47) | ALDH1A1AOX1TUBB1TUBB4ATUBB | |
| SCHEMBL3662594 | 0.74 | CNR1 (0.50) | GAAALDH1A1AOX1TUBB1TUBB4A | |
| SCHEMBL2946295 | 0.73 | CHEK1 (0.50) | ALDH1A1HTTMAPTCYP3A4LMNA | |
| SCHEMBL2946298 | 0.73 | CHEK1 (0.50) | ALDH1A1HTTMAPTCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |