Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535890 | 0.86 | SLC13A5 (0.44) | GAAALDH1A1SLC13A5 | |
| SCHEMBL6826197 | 0.83 | ALDH1A1 (0.49) | GAAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL6828426 | 0.83 | CYP2C19 (0.55) | GAAALDH1A1MAPT | |
| SCHEMBL3662594 | 0.80 | CNR1 (0.50) | GAACNR1CNR2ALDH1A1TSHR | |
| SCHEMBL19261801 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL6336769 | 0.80 | CA5A (0.41) | ALDH1A1SLC13A5MAPT | |
| SCHEMBL7603025 | 0.79 | GAA (0.50) | GAAALDH1A1TSHRNFKB1AOX1 | |
| SCHEMBL5890020 | 0.78 | ALDH1A1 (0.50) | GAACNR1CNR2ALDH1A1TSHR | |
| SCHEMBL17963707 | 0.78 | GAA (0.49) | GAAALDH1A1TSHRNFKB1AOX1 | |
| SCHEMBL3661439 | 0.78 | CNR1 (0.58) | CNR1CNR2TSHRNFKB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014972-A1 | Novel intermediate for sweetener with high sweetness and process for producing the same | AJINOMOTO CO., INC. (JP) | 2005-01-20 | — | — | US | claimed |
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | claimed |
| US-20040133027-A1 | Novel intermediate for sweetener with high sweetness and process for producing the same | AJINOMOTO CO., INC. (JP) | 2004-07-08 | — | — | US | claimed |
| US-20030216592-A1 | Novel intermediate for sweetener with high sweetness and process forproducing the same | AJINOMOTO CO., INC. (JP) | 2003-11-20 | — | — | US | claimed |
| CN-1391553-A | Novel intermediate for sweetener with high sweetness and process for producing the same | AJINOMOTO KK (JP) | 2003-01-15 | — | — | CN | claimed |
| US-20020132032-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2002-09-19 | — | — | US | claimed |
| EP-1236713-A1 | NOVEL INTERMEDIATE FOR SWEETENER WITH HIGH SWEETNESS AND PROCESS FOR PRODUCING THE SAME | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | claimed |
| EP-1219633-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | claimed |
| US-20050014972-A1 | Novel intermediate for sweetener with high sweetness and process for producing the same | AJINOMOTO CO., INC. (JP) | 2005-01-20 | — | — | US | disclosed |
| CN-1566141-A | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO KK (JP) | 2005-01-19 | — | — | CN | disclosed |
| CN-1566141-A | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO KK (JP) | 2005-01-19 | — | — | CN | disclosed |
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| EP-1219633-A4 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | AJINOMOTO KK (JP) | 2004-10-20 | — | — | EP | disclosed |
| EP-1236713-A4 | NOVEL INTERMEDIATE FOR SWEETENER WITH HIGH SWEETNESS AND PROCESS FOR PRODUCING THE SAME | AJINOMOTO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-1236713-A1 | NOVEL INTERMEDIATE FOR SWEETENER WITH HIGH SWEETNESS AND PROCESS FOR PRODUCING THE SAME | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| EP-1236713-A1 | NOVEL INTERMEDIATE FOR SWEETENER WITH HIGH SWEETNESS AND PROCESS FOR PRODUCING THE SAME | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| EP-1219633-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1219633-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001038297-A1 | NOVEL INTERMEDIATE FOR SWEETENER WITH HIGH SWEETNESS AND PROCESS FOR PRODUCING THE SAME | AJINOMOTO CO., INC. (JP) | 2001-05-31 | — | — | WO | disclosed |
| WO-2001027142-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | AJINOMOTO CO., INC. (JP) | 2001-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014972-A1 | Novel intermediate for sweetener with high sweetness and process for producing the same | PCMT1, PSAT1, DPP4 | GAA 648/4885CNR1 4664/4885CNR2 4623/4885 |
| US-20030216592-A1 | Novel intermediate for sweetener with high sweetness and process forproducing the same | PCMT1, PSAT1, MLYCD | GAA 1473/4885CNR1 4422/4885CNR2 4400/4885 |
| US-20040133027-A1 | Novel intermediate for sweetener with high sweetness and process for producing the same | PCMT1, PSAT1, DNPEP | GAA 779/4885CNR1 4592/4885CNR2 4545/4885 |
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | IAPP, DPP4, SI | GAA 897/4885CNR1 4741/4885CNR2 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.