Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PYGL | P06737 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602221 | 0.92 | PYGM (0.36) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7601200 | 0.91 | TDP1 (0.36) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7602722 | 0.90 | RAB9A (0.39) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7601975 | 0.90 | TDP1 (0.39) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7607368 | 0.85 | PYGM (0.37) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL8105309 | 0.84 | SMN1; SMN2 (0.40) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7602542 | 0.84 | MAPT (0.38) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7601939 | 0.82 | TDP1 (0.38) | TDP1RAB9AL3MBTL1PYGMKMT2A | |
| SCHEMBL7598003 | 0.78 | ALDH1A1 (0.40) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 | |
| SCHEMBL7598963 | 0.76 | ALDH1A1 (0.40) | CACNA1HCACNA1BTDP1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |