Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13301217 | 0.87 | TSHR (0.37) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL304323 | 0.85 | MEN1 (0.32) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL12763775 | 0.84 | CA12 (0.43) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL14230113 | 0.84 | CA1 (0.40) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL304559 | 0.82 | MC4R (0.35) | ALDH1A1LMNAMEN1KMT2ACA12 | |
| SCHEMBL14200284 | 0.81 | MMP8 (0.34) | ALDH1A1MAPTSMN1; SMN2MMP8 | |
| SCHEMBL25567933 | 0.81 | ALDH1A1 (0.34) | ALDH1A1LMNAMEN1KMT2ACA12 | |
| SCHEMBL304558 | 0.81 | MEN1 (0.33) | ALDH1A1LMNAMEN1KMT2ACA12 | |
| SCHEMBL11419403 | 0.79 | CA12 (0.43) | ALDH1A1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL10087929 | 0.79 | CA12 (0.46) | ALDH1A1LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344154-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20100145063-A1 | 2- thioethenyl substituted carbapenem derivatives | MARUYAMA TAKAHISA | 2010-06-10 | — | — | US | disclosed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-6448412-B1 | COMBINATORIAL CHEMISTRY LIBRARIES | SPHERE BIOSYSTEMS, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6399785-B1 | BIOSYNTHESIS; LIBRARY OF COMPOUNDS; DRUGS | C-SIXTY, INC. (CA) | 2002-06-04 | — | — | US | disclosed |
| US-6162926-A | Multi-substituted fullerenes and methods for their preparation and characterization | SPHERE BIOSYSTEMS, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| WO-1996036631-A1 | MULTIPLY-SUBSTITUTED FULLERENES AND METHODS FOR THEIR PREPARATION AND CHARACTERIZATION | SPHERE BIOSYSTEMS, INC. (US) | 1996-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145063-A1 | 2- thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, TPMT | ALDH1A1 1218/4885LMNA 1005/4885HSD17B10 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.