Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6020341 | 0.78 | POLB (0.50) | POLBALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL11568815 | 0.77 | NPC1 (0.50) | POLBALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7096077 | 0.76 | GAA (0.49) | ALDH1A1NPSR1RAB9AMEN1KMT2A | |
| SCHEMBL28643707 | 0.76 | NPC1 (0.50) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL1339981 | 0.71 | NPC1 (0.46) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL437416 | 0.69 | MEN1 (0.59) | ALDH1A1RAB9AMEN1KMT2ACTSS | |
| SCHEMBL4878105 | 0.69 | NPSR1 (0.50) | POLBALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL31284828 | 0.69 | ALDH1A1 (0.46) | POLBALDH1A1NPSR1CTSSCTSL | |
| SCHEMBL5412087 | 0.69 | DHODH (0.40) | NPC1RAB9ACTSSCTSLCTSK | |
| SCHEMBL16179158 | 0.67 | ALDH1A1 (0.57) | POLBALDH1A1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | HALE JEFFREY J (US) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | CCR5, CCR1, CXCR1 | POLB 744/4885ALDH1A1 2943/4885NPSR1 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.