SCHEMBL7603541

SCHEMBL7603541

CCC(C)OC(=O)NCCC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.40
RNPEP Q9H4A4 2/20 0.40
DNPEP Q9ULA0 2/20 0.40
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
GAA P10253 1/20 0.38
NPC1 O15118 2/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 2/20 0.36
ALOX15 P16050 1/20 0.36
CNR1 P21554 1/20 0.36
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.35
BRD4 O60885 1/20 0.34
LMNA P02545 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419405 0.84 CHRNB2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA4L3MBTL1
SCHEMBL10874284 0.82 CHRNB2 (0.45) RAB9ASMN1; SMN2CHRNB2CHRNB4CHRNA3
SCHEMBL12787082 0.82 ANPEP (0.43) ANPEPRNPEPDNPEPRAB9ASMN1; SMN2
SCHEMBL10972245 0.81 ACHE (0.55) ALOX15ALDH1A1KMT2A
SCHEMBL19343058 0.80 ANPEP (0.37) ANPEPRNPEPDNPEPRAB9ASMN1; SMN2
SCHEMBL15759434 0.80 CYP2D6 (0.46) RAB9ASMN1; SMN2GAAHPGDCNR1
SCHEMBL5638554 0.79 SMN1; SMN2 (0.44) SMN1; SMN2CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL8435882 0.78 EPHX1 (0.61)
SCHEMBL5949707 0.77 EPHX1 (0.48) ANPEPRNPEPDNPEPRAB9ASMN1; SMN2
SCHEMBL21674070 0.77 ANPEP (0.40) ANPEPRNPEPDNPEPRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448412-B1 COMBINATORIAL CHEMISTRY LIBRARIES SPHERE BIOSYSTEMS, INC. 2002-09-10 US disclosed
US-6399785-B1 BIOSYNTHESIS; LIBRARY OF COMPOUNDS; DRUGS C-SIXTY, INC. (CA) 2002-06-04 US disclosed
US-6162926-A Multi-substituted fullerenes and methods for their preparation and characterization SPHERE BIOSYSTEMS, INC. (US) 2000-12-19 US disclosed
WO-1996036631-A1 MULTIPLY-SUBSTITUTED FULLERENES AND METHODS FOR THEIR PREPARATION AND CHARACTERIZATION SPHERE BIOSYSTEMS, INC. (US) 1996-11-21 WO disclosed